PRF vs. PRP in Microneedling: Understanding the Superior Growth Factors

PRF offers 3x more growth factors than PRP for natural skin rejuvenation during microneedling treatments. Learn why PRF is becoming the preferred choice at West Asheville Aesthetics & Wellness.
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PRF vs. PRP in Microneedling: Understanding the Superior Growth Factors

PRF vs. PRP in Microneedling: Understanding the Superior Growth Factors

The Evolution of Regenerative Skincare Treatments in Asheville

At West Asheville Aesthetics & Wellness, we’ve witnessed a significant shift in regenerative skincare treatments. While PRP (Platelet-Rich Plasma) has been a trusted option for years, PRF (Platelet-Rich Fibrin) is quickly becoming the preferred choice for those seeking superior results. Both treatments use your body’s natural healing abilities, but PRF offers distinct advantages that can transform your microneedling experience. If you’re considering advanced skin rejuvenation in Asheville, understanding the difference between these powerful treatments can help you make an informed decision about which option might better address your specific skincare concerns.

What Are PRP and PRF Treatments?

Both PRP and PRF treatments begin with a simple blood draw from your arm, similar to a routine blood test. The key difference lies in what happens next. With PRP, your blood is processed in a centrifuge with an anticoagulant to separate the platelets from other blood components. These platelets are then concentrated and applied to the skin during microneedling.

PRF takes this process further. Your blood is centrifuged at a slower speed without anticoagulants, resulting in a fibrin matrix rich with platelets, white blood cells, and stem cells. This creates a natural scaffold that releases growth factors more gradually and effectively than PRP. The absence of anticoagulants means PRF contains more of your body’s natural healing components intact.

Why PRF Delivers Superior Results

Triple the Growth Factor Concentration

The most compelling advantage of PRF is its significantly higher concentration of growth factors—approximately three times more than traditional PRP. These growth factors are the essential proteins that stimulate cell growth, tissue regeneration, and collagen production. With PRF, your skin receives a more potent dose of these rejuvenating elements, enhancing results for concerns like fine lines, texture irregularities, and overall skin tone.

Longer-Lasting Release of Healing Elements

Unlike PRP, which releases growth factors quickly and depletes within hours, PRF creates a fibrin matrix that acts as a time-release mechanism. This matrix gradually releases growth factors over 7-10 days, providing sustained healing support to your skin. This extended release means your skin receives continuous regenerative benefits throughout its natural healing process following microneedling.

More Natural Composition

PRF processing avoids artificial anticoagulants, preserving the natural state of your blood components. This means white blood cells, stem cells, and other healing elements remain intact and functional. The result is a truly natural approach to skin rejuvenation that works in harmony with your body’s own processes rather than bypassing them.

The PRF Microneedling Experience at West Asheville Aesthetics

When you choose PRF microneedling at our inclusive Asheville medical spa, you’ll experience a carefully designed treatment protocol that maximizes results while ensuring comfort. The procedure begins with drawing a small amount of blood, which is immediately processed in our specialized centrifuge. While this occurs, a topical numbing cream is applied to your treatment area.

The microneedling portion of the treatment creates thousands of microscopic channels in your skin, activating your body’s wound healing response. Your freshly prepared PRF is then applied to these channels, where it can penetrate deeply and deliver its regenerative benefits directly where needed. The entire process typically takes about 60-90 minutes, with minimal downtime afterward.

Ideal Candidates and Expected Results

PRF microneedling is particularly effective for addressing:

Fine lines and early wrinkles
Uneven skin texture
Sun damage and hyperpigmentation
Mild skin laxity
Acne scarring
Overall skin rejuvenation

Most clients notice improved skin texture and tone within weeks of their first treatment, with continued improvement as collagen production increases. For optimal results, we typically recommend a series of 3-4 treatments spaced 4-6 weeks apart, followed by maintenance treatments every 6-12 months.

Experience the PRF Difference Today

Ready to discover how PRF can enhance your microneedling results? Our team at West Asheville Aesthetics & Wellness is here to guide you through your options and create a personalized treatment plan. Contact us today to schedule your consultation and take the first step toward naturally rejuvenated skin with the superior benefits of PRF technology.

Call us at (828) XXX-XXXX or book your appointment online. New clients receive 15% off their first treatment!


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Mon-Fri 8am - 5:30pm
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West Asheville
Aesthetics & Wellness

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Suite 201, above the restaurant, Nine Mile, and directly next to the Kava Lounge. You can enter either from the front of the building through the Kava Lounge or directly on the side door on Herron Ave.

There is free parking behind the building between 8 am and 4 pm. After 4 pm all of the parking is designated for Nine Mile.

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